Is it ‘gene therapy’?

Gene therapy : what it is , what it is not and what it will be

Gene therapy is the therapeutic procedure based on the introduction of healthy genes using recombinant DNA techniques. the first successful clinical trial of this technique was published in 1990. Despite the occurrence of adverse effects in certain clinical trials, some of them serious, both laboratories and companies are continuously developing novel materials and establishing both safer and m...

[Gene therapy: what is it and what is its use?].

Gene therapy has developed as a method of approach to the treatment of human diseases based on the transfer of genetic material to the cells of an individual. Normally, the aim of this transfer of genetic material is to re-establish a cellular function that has been abolished or is defective, to introduce a new function or to interfere with an existing function. Thus, the different gene therapy...

Thyroid function in major thalassemia patients: Is it related to height and chelation therapy?

Background: One of the most common endocrine problems in major beta-thalassemia is hypothyroidism (HT). The aim of this study was to evaluate thyroid function status in major beta-thalassemia patients older than 10 years old. Methods: This cross sectional study was carried out on thalassemia major patients registered on Thalassemia Center of Amirkola Children Hospital in Babol. A questionnaire ...

HIV-1 CCR5 gene therapy will fail unless it is combined with a suicide gene

Highly active antiretroviral therapy (ART) has successfully turned Human immunodeficiency virus type 1 (HIV-1) from a deadly pathogen into a manageable chronic infection. ART is a lifelong therapy which is both expensive and toxic, and HIV can become resistant to it. An alternative to lifelong ART is gene therapy that targets the CCR5 co-receptor and creates a population of genetically modified...

therapy for hbv infection in hemodialysis patients: is it possible?